326 Modeling dermatophytosis in reconstructed human epidermis
نویسندگان
چکیده
منابع مشابه
Reconstructed Human Epidermis: an Efficient Prediction Tool
RHE has the ultimate advantage to grow donor epidermal cells in a serumfree culture environment: after rapidly proliferating preparative keratinocyte cultures have been obtained, the yielded epidermal cells are seeded on inert filter substrates that are lifted to the air-liquid interface in a humidified-air incubator. A fully-defined nutrient medium feeds the basal cells through the filter subs...
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One of the most recent trends in skin irritation safety testing of personal care and cosmetic products, discussed in detail in this review, is the use of reconstructed human epidermis models. Some of the commercially-available models have undergone a series of validation trials, which successfully advanced them as valuable tools for industry use. On a broader perspective, the 3D models are now ...
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One of the problems of public health in Iran is mycotic inflection which its incidence is not known. The most important disease of them is dermatophytosis. In this regard, determination of various species of etiologic agent, infection source, the risk of contact to animals, and public training are necessary to perform epidemiologic studies. In this research 750 suspected samples (including 560 ...
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BACKGROUND Trichophyton rubrum represents the most common infectious fungus responsible for dermatophytosis in human, but the mechanism involved is still not completely understood. An appropriate model constructed to simulate host infection is the prerequisite to study the pathogenesis of dermatophytosis caused by T. rubrum. In this study, we intended to develop a new T. rubrum infection model ...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2016
ISSN: 0022-202X
DOI: 10.1016/j.jid.2016.06.346